You are unable to edit fields such as Distribution Channel , Division , etc in Sales Quote though the Sales Quote is in Open status.
SAP Hybris Cloud For Customer.
Reproducing the Issue
Go to Sales work center.
Go to Sales Quote view.
Open Sales Quote 123(where 123 is Sales Quote ID).
Click on Edit.
Most of the fields are greyed out and you are unable to edit these in Sales Quote.
The Approval Status of Sales Quote 123 is 'In Approval', hence you are unable to change the data.
This is the expected and correct system behavior.
Sales Quote , editable , greyed out , status , KBA , greyed out , sales quote , open , approval , LOD-LE-CQP , Customer Quote Processing , Problem