You are getting CALL_FUNCTION_SEND_ERROR runtime errors in the system (transaction ST22) with the following details:
CPIC-CALL: 'ThCMSEND' : cmRc=18 thRc=0 Statistics not active
An error occurred when executing a Remote Function Call.
CALL_FUNCTION_SEND_ERROR, dump , KBA , BC-MID-RFC , RFC , Problem
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